KLHL2 antibody

Catalogue No.:FNab04617Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KLHL2 antibody
Catalogue No.
FNab04617
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
kelch-like 2, Mayven(Drosophila)
UniProt ID
O95198
Observed MW
66 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab04617(KLHL2 antibody) at dilution of 1:500
Background
Component of a cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation(By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.