Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04553(KIF18A antibody) at dilution of 1:500
IP Result of anti-KIF18A (IP:FNab04553, 4ug; Detection:FNab04553 1:500) with Jurkat cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human liver using FNab04553(KIF18A antibody) at dilution of 1:100
Background
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.