Products
KIAA0430 antibody
- Product Name
- KIAA0430 antibody
- Catalogue No.
- FNab04532
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- KIAA0430
- Alternative Names
- LKAP antibody, MARF1 antibody
- UniProt ID
- Q9Y4F3
- Observed MW
- 192 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:200-1:1000 ; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04532(KIAA0430 Antibody) at dilution of 1:600
IP Result of anti-KIAA0430 (IP:FNab04532, 5ug; Detection:FNab04532 1:300) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab04532(KIAA0430 Antibody) at dilution of 1:50
- Background
- Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks(By similarity).
