KCNN4 antibody

Synonyms:IK1 antibody, IKCA1 antibody, KCA4 antibody, SK4 antibody
Catalogue No.:FNab04498Reactivity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KCNN4 antibody
Catalogue No.
FNab04498
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Alternative Names
IK1 antibody, IKCA1 antibody, KCA4 antibody, SK4 antibody
UniProt ID
O15554
Observed MW
48 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04498( KCNN4 Antibody) at dilution of 1:1000
Background
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).