mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04496(KCNN1 antibody) at dilution of 1:4000
Background
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin(By similarity).