KCNIP4 antibody

Category: Research Area:
Synonyms：CALP antibody, KCHIP4 antibody
Catalogue No.：FNab04489Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
KCNIP4 antibody
Catalogue No.
FNab04489
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Kv channel interacting protein 4
Alternative Names
CALP antibody, KCHIP4 antibody
UniProt ID
Q6PIL6
Observed MW
29kd
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab04489( KCNIP4 Antibody) at dilution of 1:2000
Background
Regulatory subunit of Kv4/D(Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner(PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents(PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane(PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.
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