KCNE1 antibody

Catalogue No.:FNab04482Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KCNE1 antibody
Catalogue No.
FNab04482
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
potassium voltage-gated channel, Isk-related family, member 1
UniProt ID
P15382
Observed MW
18-25kd,28-35kd
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab04482(KCNE1 antibody) at dilution of 1:500
Background
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1(PubMed:19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium(IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart(IKr).