Products
KATNB1 antibody
- Product Name
- KATNB1 antibody
- Catalogue No.
- FNab04471
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- katanin p80(WD repeat containing) subunit B 1
- Alternative Names
- KAT antibody, Katanin p80 subunit B1 antibody, KATNB1 antibody, p80 katanin antibody
- UniProt ID
- Q9BVA0
- Observed MW
- 72-80 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04471(KATNB1 antibody) at dilution of 1:300
IP Result of anti-KATNB1 antibody（IP: FNab04471, 3μg; Detection: FNab04471 1:500）with Hela cells lysate 3000μg.
- Background
- Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
