Products

KANK2 antibody

Synonyms:ANKRD25 antibody, KIAA1518 antibody, MXRA3 antibody, SIP antibody
Catalogue No.:FNab04465Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
KANK2 antibody
Catalogue No.
FNab04465
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
KN motif and ankyrin repeat domains 2
Alternative Names
ANKRD25 antibody, KIAA1518 antibody, MXRA3 antibody, SIP antibody
UniProt ID
Q63ZY3
Observed MW
95 kDa
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab04465(KANK2 antibody) at dilution of 1:800
Background
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity).