Products
ITPA antibody
- Product Name
- ITPA antibody
- Catalogue No.
- FNab04420
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- inosine triphosphatase(nucleoside triphosphate pyrophosphatase)
- Alternative Names
- C20orf37 antibody
- UniProt ID
- Q9BY32
- Observed MW
- 22 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab04420(ITPA antibody) at dilution of 1:1000
IP Result of anti-ITPA (IP:FNab04420, 4ug; Detection:FNab04420 1:1000) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab04420(ITPA Antibody) at dilution of 1:50
- Background
- Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate(ITP), deoxyinosine triphosphate(dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate(dHAPTP) and xanthosine 5'-triphosphate(XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy-and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
