Products
IRF4 antibody
- Product Name
- IRF4 antibody
- Catalogue No.
- FNab04390
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interferon regulatory factor 4
- Alternative Names
- MUM1 antibody
- UniProt ID
- Q15306
- Observed MW
- 52 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04390(IRF4 Antibody) at dilution of 1:1000
IP Result of anti-MUM1/IRF4 (IP:FNab04390, 3ug; Detection:FNab04390 1:500) with mouse spleen tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab04390(IRF4 antibody) at dilution of 1:50
- Background
- Transcriptional activator. Binds to the interferon-stimulated response element(ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes(By similarity).
