IRF2BP1 antibody

Category: Research Area:
Catalogue No.：FNab04387Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC, IF, IP
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
IRF2BP1 antibody
Catalogue No.
FNab04387
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
interferon regulatory factor 2 binding protein 1
UniProt ID
Q8IU81
Observed MW
62-72 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04387(IRF2BP1 antibody) at dilution of 1:800
IP Result of anti-IRF2BP1 (IP:FNab04387, 4ug; Detection:FNab04387 1:500) with HEK-293 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab04387(IRF2BP1 antibody) at dilution of 1:50
Background
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
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