ING2 antibody

Synonyms:ING1L antibody
Catalogue No.:FNab04310Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ING2 antibody
Catalogue No.
FNab04310
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
inhibitor of growth family, member 2
Alternative Names
ING1L antibody
UniProt ID
Q9H160
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04310(ING2 antibody) at dilution of 1:400
IP Result of anti-ING2 (IP:FNab04310, 3ug; Detection:FNab04310 1:500) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab04310(ING2 antibody) at dilution of 1:50
Background
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides(PtdInsPs).