IMPDH2 antibody

Synonyms:IMPD2 antibody
Catalogue No.:FNab04303Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IMPDH2 antibody
Catalogue No.
FNab04303
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
IMP(inosine monophosphate) dehydrogenase 2
Alternative Names
IMPD2 antibody
UniProt ID
P12268
Observed MW
56 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab04303(IMPDH2 antibody) at dilution of 1:400
IP Result of anti-IMPDH2 (IP:FNab04303, 3ug; Detection:FNab04303 1:800) with K-562 cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04303(IMPDH2 antibody) at dilution of 1:100
Background
Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.