Products
IMPDH1 antibody
- Product Name
- IMPDH1 antibody
- Catalogue No.
- FNab04302
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- IMP(inosine monophosphate) dehydrogenase 1
- Alternative Names
- IMPD1 antibody
- UniProt ID
- P20839
- Observed MW
- 53-60 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04302(IMPDH1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human ovary tumor slide using FNab04302(IMPDH1 Antibody) at dilution of 1:50
- Background
- Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
