Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04275(IL37 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab04275(IL37 antibody) at dilution of 1:200
Background
Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.