IL17RE antibody

Catalogue No.:FNab04232Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IL17RE antibody
Catalogue No.
FNab04232
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
interleukin 17 receptor E
UniProt ID
Q8NFR9
Observed MW
75 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04232(IL17RE antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab04232(IL17RE antibody) at dilution of 1:50
Background
Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.