Products
IL11 antibody
- Product Name
- IL11 antibody
- Catalogue No.
- FNab04216
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 11
- Alternative Names
- Adipogenesis inhibitory factor antibody, AGIF antibody, IL 11 antibody, IL11 antibody, interleukin 11 antibody, Oprelvekin antibody
- UniProt ID
- P20809
- Observed MW
- 25 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:1000
Validated Images
human plasma tissue were subjected to SDS PAGE followed by western blot with FNab04216(IL11 Antibody) at dilution of 1:500
- Background
- Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production(PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation(PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
