Products

anti- IL10RB antibody

FNab04215 Catalogue No.
Synonyms
CRFB4, D21S58, D21S66
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- IL10RB antibody
Catalogue No.
FNab04215
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.
Immunogen Information
Immunogen
interleukin 10 receptor, beta
Synonyms
CRFB4, D21S58, D21S66
Observed MW
42-45 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Uniprot information
UniProt ID
Q08334
Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04215(IL10RB antibody) at dilution of 1:500