IGSF8 antibody

Synonyms:CD81P3 antibody, EWI2 antibody, KCT4 antibody
Catalogue No.:FNab04193Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IGSF8 antibody
Catalogue No.
FNab04193
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
immunoglobulin superfamily, member 8
Alternative Names
CD81P3 antibody, EWI2 antibody, KCT4 antibody
UniProt ID
Q969P0
Observed MW
70kd
Application
Tested Applications
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab04193(IGSF8 antibody) at dilution of 1:500
IP Result of anti-IGSF8 (IP:FNab04193, 3ug; Detection:FNab04193 1:500) with mouse brain tissue lysate 5000ug.
Background
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.