Products
IGFBP3 antibody
- Product Name
- IGFBP3 antibody
- Catalogue No.
- FNab04178
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- insulin-like growth factor binding protein 3
- Alternative Names
- BP 53 antibody, IBP 3 antibody, IBP3 antibody, IGF binding protein 3 antibody, IGFBP 3 antibody, IGFBP3 antibody
- UniProt ID
- P17936
- Observed MW
- 32kd
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:500; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
A2780 cells were subjected to SDS PAGE followed by western blot with FNab04178(IGFBP3 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using FNab04178(IGFBP3 antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab04178 (IGFBP3 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
