Products
IFITM2 antibody
- Product Name
- IFITM2 antibody
- Catalogue No.
- FNab04142
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interferon induced transmembrane protein 2
- Alternative Names
- DSPA2c antibody, IFITM2 antibody
- UniProt ID
- Q01629
- Observed MW
- 15kd
Application
- Tested Applications
- ELISA, IP, IHC, IF, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab04142(IFITM2 Antibody) at dilution of 1:2000
IP Result of anti-IFITM2 (IP:FNab04142, 3ug; Detection:FNab04142 1:300) with HepG2 cells lysate 1720ug.
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab04142(IFITM2 Antibody) at dilution of 1:50
- Background
- IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
