Products
IFIT5 antibody
- Product Name
- IFIT5 antibody
- Catalogue No.
- FNab04139
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interferon-induced protein with tetratricopeptide repeats 5
- Alternative Names
- ISG58 antibody, RI58 antibody
- UniProt ID
- Q13325
- Observed MW
- 56-58 kDa, 48 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab04139(IFIT5 antibody) at dilution of 1:200
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using FNab04139(IFIT5 Antibody) at dilution of 1:50
- Background
- Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
