rat heart tissue were subjected to SDS PAGE followed by western blot with FNab04102(ICAM-1 antibody) at dilution of 1:800
IP Result of anti-ICAM-1 (IP:FNab04102, 4ug; Detection:FNab04102 1:1000) with Raji cells lysate 1320ug.
Immunohistochemistry of paraffin-embedded mouse lung using FNab04102(ICAM-1 antibody) at dilution of 1:50
Background
ICAM-1(CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues(PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin(PMID: 3086451; 9694714; 15979056).