Icam-1 antibody

Synonyms:BB2 antibody, CD54 antibody, ICAM 1 antibody, ICAM1 antibody, ICAM-1 antibody, P3.58 antibody
Catalogue No.:FNab04102Reactivity:Mouse, Rat
Host:RabbitTested Application:ELISA, IF, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Icam-1 antibody
Catalogue No.
FNab04102
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
intercellular adhesion molecule 1
Alternative Names
BB2 antibody, CD54 antibody, ICAM 1 antibody, ICAM1 antibody, ICAM-1 antibody, P3.58 antibody
UniProt ID
P05362
Observed MW
85-95 kDa
Application
Tested Applications
ELISA, IF, WB, IHC, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
rat heart tissue were subjected to SDS PAGE followed by western blot with FNab04102(ICAM-1 antibody) at dilution of 1:800
IP Result of anti-ICAM-1 (IP:FNab04102, 4ug; Detection:FNab04102 1:1000) with Raji cells lysate 1320ug.
Immunohistochemistry of paraffin-embedded mouse lung using FNab04102(ICAM-1 antibody) at dilution of 1:50
Background
ICAM-1(CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues(PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin(PMID: 3086451; 9694714; 15979056).