Products
HSP90 antibody
Category:
Research Area:
Synonyms: | HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody | ||
Catalogue No.: | FNab04051 | Reactivity: | Human, Mouse, Rat |
Host: | Rabbit | Tested Application: | ELISA, IF, IHC, IP, WB, FC |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- Product Name
- HSP90 antibody
- Catalogue No.
- FNab04051
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- heat shock protein 90kDa alpha(cytosolic), class A member 1
- Alternative Names
- HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody
- UniProt ID
- P07900
- Observed MW
- 90 kDa
Application
- Tested Applications
- ELISA, IF, IHC, IP, WB, FC
- Recommended dilution
- WB: 1:1000-1:6000IP:1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04051(HSP90 Antibody) at dilution of 1:3000
IP Result of anti-HSP90 (IP: FNab04051, 4ug; Detection: FNab04051 1:500) with K-562 cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer using FNab04051(HSP90 antibody) at dilution of 1:50
- Background
- HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.