Products
HSD17B6 antibody
- Product Name
- HSD17B6 antibody
- Catalogue No.
- FNab04027
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- hydroxysteroid(17-beta) dehydrogenase 6 homolog(Mouse)
- Alternative Names
- RODH antibody, SDR9C6 antibody
- UniProt ID
- O14756
- Observed MW
- 33-35kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab04027(HSD17B6 antibody) at dilution of 1:200
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04027(HSD17B6 antibody) at dilution of 1:50
- Background
- NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
