HRH2 antibody

Catalogue No.:FNab04011Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HRH2 antibody
Catalogue No.
FNab04011
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
histamine receptor H2
UniProt ID
P25021
Observed MW
59kd,69kd
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab04011(HRH2 antibody) at dilution of 1:500
Background
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase(PKC) signaling pathway(By similarity).