HPS4 antibody

Synonyms:KIAA1667 antibody
Catalogue No.:FNab04000Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IF, IP, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HPS4 antibody
Catalogue No.
FNab04000
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Hermansky-Pudlak syndrome 4
Alternative Names
KIAA1667 antibody
UniProt ID
Q9NQG7
Observed MW
70 kDa and 90 kDa
Application
Tested Applications
ELISA, WB, IF, IP, IHC
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab04000(HPS4 antibody) at dilution of 1:200
IP result of anti-HPS4 (FNab04000 for IP and Detection) with HeLa cell lysate.
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab04000(HPS4 Antibody) at dilution of 1:50
Background
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).