Products
HOPX antibody
- Product Name
- HOPX antibody
- Catalogue No.
- FNab03970
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- HOP homeobox
- Alternative Names
- HOD antibody, HOP antibody, LAGY antibody, NECC1 antibody, OB1 antibody
- UniProt ID
- Q9BPY8
- Observed MW
- 8-12kd
Application
- Tested Applications
- ELISA, IF, WB
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:50-1:200
Validated Images
mouse brain were subjected to SDS PAGE followed by western blot with FNab03970(HPOX antibody) at dilution of 1:1000
- Background
- Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
