HOMER2 antibody

Catalogue No.:FNab03964Reactivity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HOMER2 antibody
Catalogue No.
FNab03964
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
homer homolog 2(Drosophila)
UniProt ID
Q9NSB8
Observed MW
39 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
U2OS cells were subjected to SDS PAGE followed by western blot with FNab03964(HOMER2 antibody) at dilution of 1:2000
Background
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses(PubMed:9808459). Required for normal hearing(PubMed:25816005).