HJURP antibody

Synonyms:FAKTS antibody, FLEG1 antibody, URLC9 antibody
Catalogue No.:FNab03892Reactivity:Human
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HJURP antibody
Catalogue No.
FNab03892
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Holliday junction recognition protein
Alternative Names
FAKTS antibody, FLEG1 antibody, URLC9 antibody
UniProt ID
Q8NCD3
Observed MW
70kd,83-85kd
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab03892(HJURP antibody) at dilution of 1:800
Background
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.