Products
HIVEP1 antibody
Category:
Research Area:
Synonyms: | Zinc finger protein 40|Cirhin interaction protein (CIRIP)|Gate keeper of apoptosis-activating protein (GAAP)|Human immunodeficiency virus type I enhancer-binding protein 1 (HIV-EP1)|Major histocompatibility complex-binding protein 1 (MBP-1)|Positive regulatory domain II-binding factor 1 (PRDII-BF1)|HIVEP1|ZNF40 antibody | ||
Catalogue No.: | FNab03891 | Reactivity: | Human |
Host: | Rabbit | Tested Application: | ELISA, IHC |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- Product Name
- HIVEP1 antibody
- Catalogue No.
- FNab03891
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- human immunodeficiency virus type I enhancer binding protein 1
- Alternative Names
- Zinc finger protein 40|Cirhin interaction protein (CIRIP)|Gate keeper of apoptosis-activating protein (GAAP)|Human immunodeficiency virus type I enhancer-binding protein 1 (HIV-EP1)|Major histocompatibility complex-binding protein 1 (MBP-1)|Positive regulatory domain II-binding factor 1 (PRDII-BF1)|HIVEP1|ZNF40 antibody
- UniProt ID
- P15822
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human stomach tissue using FNab03891(HIVEP1 Antibody) at dilution of 1:50
- Background
- This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS(IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.