Products
Histone-H3 antibody
- Product Name
- Histone-H3 antibody
- Catalogue No.
- FNab03890
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- histone cluster 2, H3a
- Alternative Names
- H3/n antibody, H3/o antibody, H3F2 antibody, H3FM antibody, HIST2H3A antibody, HIST2H3C antibody, HIST2H3D antibody, histone cluster 2 antibody, H3a antibody, Histone H3 antibody, Histone H3.2 antibody, Histone H3/m antibody, Histone H3/o antibody
- UniProt ID
- Q71DI3
- Observed MW
- 15-17 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:200; IF: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03890(Histone-H3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03890(Histone-H3 Antibody) at dilution of 1:50
Immunofluorescent analysis of HEK-293 cells using FNab03890 (Histone-H3 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
- Background
- HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.
