Products

anti- Hemoglobin alpha antibody

FNab03825 Catalogue No.
Synonyms
Alpha globin, HBA1, HBA2, Hemoglobin a, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin, alpha 1
Host
Rabbit
Reactivity
Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- Hemoglobin alpha antibody
Catalogue No.
FNab03825
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Immunogen Information
Immunogen
hemoglobin, alpha 1
Synonyms
Alpha globin, HBA1, HBA2, Hemoglobin a, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin, alpha 1
Observed MW
13 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Uniprot information
UniProt ID
P69905
Images
Immunohistochemistry of paraffin-embedded mouse heart using FNab03825 (Hemoglobin alpha antibody) at dilution of 1:100
mouse liver were subjected to SDS PAGE followed by western blot with FNab03825 (Hemoglobin alpha antibody) at dilution of 1:1000