Products
GSPT2 antibody
- Product Name
- GSPT2 antibody
- Catalogue No.
- FNab03681
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- G1 to S phase transition 2
- Alternative Names
- ERF3B antibody
- UniProt ID
- Q8IYD1
- Observed MW
- 69 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03681(GSPT2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human colon cancer using FNab03681(GSPT2 antibody) at dilution of 1:100
- Background
- Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome-and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.
