SGC-7901 cells were subjected to SDS PAGE followed by western blot with FNab03680(GSPT1 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03680(GSPT1 antibody) at dilution of 1:100
Background
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.