GSPT1 antibody

Synonyms:ERF3A antibody
Catalogue No.:FNab03680Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GSPT1 antibody
Catalogue No.
FNab03680
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
G1 to S phase transition 1
Alternative Names
ERF3A antibody
UniProt ID
P15170
Observed MW
80 kDa ; 84 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
SGC-7901 cells were subjected to SDS PAGE followed by western blot with FNab03680(GSPT1 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03680(GSPT1 antibody) at dilution of 1:100
Background
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.