Products
GSK3B antibody
- Product Name
- GSK3B antibody
- Catalogue No.
- FNab03676
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glycogen synthase kinase 3 beta
- Alternative Names
- GSK 3 beta antibody, GSK3 beta antibody, GSK3A B antibody, GSK3B antibody, GSK-3B antibody, GSK3B 216P antibody, gsk3beta antibody
- UniProt ID
- P49841
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab03676(GSK3B antibody) at dilution of 1:1000
IP Result of anti-GSK3B (IP: FNab03676, 3ug; Detection: FNab03676 1:500) with HeLa cells lysate 800ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab03676(GSK3B Antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab03676 (GSK3B antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Glycogen synthase kinase-3(GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.
