GSK3B antibody

Synonyms:GSK 3 beta antibody, GSK3 beta antibody, GSK3A B antibody, GSK3B antibody, GSK-3B antibody, GSK3B 216P antibody, gsk3beta antibody
Catalogue No.:FNab03674Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GSK3B antibody
Catalogue No.
FNab03674
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glycogen synthase kinase 3 beta
Alternative Names
GSK 3 beta antibody, GSK3 beta antibody, GSK3A B antibody, GSK3B antibody, GSK-3B antibody, GSK3B 216P antibody, gsk3beta antibody
UniProt ID
P49841
Observed MW
50 kDa
Application
Tested Applications
ELISA, WB, IF, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:20-1:200
Validated Images
mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab03674(GSK3B antibody) at dilution of 1:300
IP Result of anti-GSK3B (IP: FNab03674, 4ug; Detection: FNab03674 1:1000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab03674(GSK3B Antibody) at dilution of 1:50
Background
Glycogen synthase kinase-3(GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.