Products
GSDMD antibody
- Product Name
- GSDMD antibody
- Catalogue No.
- FNab03670
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- gasdermin D
- Alternative Names
- DF5L antibody, DFNA5L antibody, FKSG10 antibody, FLJ12150 antibody, gasdermin D antibody, GSDMD antibody, GSDMDC1 antibody
- UniProt ID
- P57764
- Observed MW
- 50-53 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03670(GSDMD Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skin using FNab03670(GSDMD antibody) at dilution of 1:50
- Background
- GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
