GPSM2 antibody

Synonyms:LGN antibody
Catalogue No.:FNab03618Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GPSM2 antibody
Catalogue No.
FNab03618
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
G-protein signaling modulator 2(AGS3-like, C. elegans)
Alternative Names
LGN antibody
UniProt ID
P81274
Observed MW
66-70 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03618(GPSM2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab03618(GPSM2 antibody) at dilution of 1:50
Background
Plays an important role in mitotic spindle pole organization via its interaction with NUMA1(PubMed:15632202, PubMed:21816348). Plays an important role in asymmetric cell divisions(PubMed:21816348). Has guanine nucleotide dissociation inhibitor(GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity(By similarity).