Products
GP repeat antibody
- Product Name
- GP repeat antibody
- Catalogue No.
- FNab03570
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- GP repeat
- Alternative Names
- C9RAN antibody, GGGCC antibody, GP repeat antibody, GPGPGPGP antibody, poly GP antibody, poly PG antibody
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Recombinant proteins which contains GP repeat sequence were subjected to SDS PAGE followed by western blot with FNab03570(GP repeat Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human bain using FNab03570(GP repeat antibody) at dilution of 1:100
- Background
- The C9orf72 "GGGGCC" repeat sequence codes five repeat peptide "GA repeat; GAGAGAGAGA", "GP repeat; GPGPGPGPG", "GR repeat; GRGRGRGRG", "AP repeat; APAPAPAPA" and "PR repeat; PRPRPRPRP". It was described previously that aggregated forms of poly-GA and poly-GP proteins do not enter the separation gel (PMID: 26374446). This antibody is used to detect the GP repeated sequence. The recombinant protein with 6*His tag or GST tag which contains the sequence “GPGPGPGPG” were used to detect this antibody.
