K-562 cells were subjected to SDS PAGE followed by western blot with FNab03562(GOPC antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab03562(GOPC antibody) at dilution of 1:50
Background
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.