mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab03533(GNAI3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab03533(GNAI3 antibody) at dilution of 1:50
Background
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.