GNAI2 antibody

Synonyms:GNAI2B antibody, GIP antibody, H_LUCA15.1 antibody, H_LUCA16.1 antibody
Catalogue No.:FNab03532Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GNAI2 antibody
Catalogue No.
FNab03532
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 2
Alternative Names
GNAI2B antibody, GIP antibody, H_LUCA15.1 antibody, H_LUCA16.1 antibody
UniProt ID
P04899
Observed MW
35-40 kDa
Application
Tested Applications
ELISA, WB, IF, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03532(GNAI2 antibody) at dilution of 1:1000
IP Result of anti-GNAI2 (IP: FNab03532, 4ug; Detection: FNab03532 1:1000) with mouse kidney tissue lysate 3000ug.
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab03532(GNAI2 Antibody) at dilution of 1:50
Immunofluorescent analysis of Hela cells, using FNab03532(GNAI2 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG.
Background
Guanine nucleotide-binding proteins(G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.