Products
GM2A antibody
- Product Name
- GM2A antibody
- Catalogue No.
- FNab03518
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 9C9
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- GM2 ganglioside activator
- Alternative Names
- Ganglioside GM2 activator antibody, GM2 AP antibody, GM2 ganglioside activator antibody, GM2A antibody, SAP 3 antibody
- UniProt ID
- P17900
- Observed MW
- 22 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:1000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab03518(GM2A Antibody) at dilution of 1:500
- Background
- The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
