Products
GLRA3 antibody
- Product Name
- GLRA3 antibody
- Catalogue No.
- FNab03488
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glycine receptor, alpha 3
- UniProt ID
- O75311
- Observed MW
- 54kd
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03488(GLRA3 antibody) at dilution of 1:200
- Background
- Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure(By similarity). Plays an important role in the down-regulation of neuronal excitability(By similarity). Contributes to the generation of inhibitory postsynaptic currents(By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels(By similarity). Plays a role in cellular responses to ethanol(By similarity).
