Products
GLRA2 antibody
- Product Name
- GLRA2 antibody
- Catalogue No.
- FNab03487
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glycine receptor, alpha 2
- Alternative Names
- GLR antibody, GLRA2 antibody, glycine receptor antibody, alpha 2 antibody
- UniProt ID
- P23416
- Observed MW
- 48 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
Rat brain tissue were subjected to SDS PAGE followed by western blot with FNab03487(GLRA2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab03487(GLRA2 Antibody) at dilution of 1:50
- Background
- Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine(PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Plays a role in cellular responses to ethanol(PubMed:23895467).
