GBP5 antibody

Category: Research Area:
Catalogue No.：FNab03376Reactivity：Human
Host：RabbitTested Application：ELISA, IHC, IF, WB, FC
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
GBP5 antibody
Catalogue No.
FNab03376
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
guanylate binding protein 5
UniProt ID
Q96PP8
Observed MW
65 kDa, 55 kDa
Application
Tested Applications
ELISA, IHC, IF, WB, FC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
U-937 cells were subjected to SDS PAGE followed by western blot with FNab03376(GBP5 Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03376(GBP5 antibody) at dilution of 1:100
Background
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents(PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP(PubMed:20180847).
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