Products
GAB2 antibody
- Product Name
- GAB2 antibody
- Catalogue No.
- FNab03272
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- GRB2-associated binding protein 2
- Alternative Names
- KIAA0571 antibody
- UniProt ID
- Q9UQC2
- Observed MW
- 70-74 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab03272(GAB2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03272(GAB2 Antibody) at dilution of 1:50
- Background
- Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
