GAA antibody

Synonyms:Acid maltase antibody, Aglucosidase alfa antibody, GAA antibody, glucosidase antibody, alpha; acid antibody, LYAG antibody, Lysosomal alpha glucosidase antibody
Catalogue No.:FNab03271Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GAA antibody
Catalogue No.
FNab03271
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Lysosomal alpha-glucosidase
Alternative Names
Acid maltase antibody, Aglucosidase alfa antibody, GAA antibody, glucosidase antibody, alpha; acid antibody, LYAG antibody, Lysosomal alpha glucosidase antibody
UniProt ID
P10253
Observed MW
70-76 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab03271(GAA antibody) at dilution of 1:600
IP Result of anti-GAA (IP:FNab03271, 4ug; Detection:FNab03271 1:600) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab03271(GAA antibody) at dilution of 1:50
Background
GAA(Alpha-1,4-glucosidase) is a lysosomal enzyme involved in the degradation of glycogen within cellular vacuoles. After translation, GAA undergoes proteolytic processing to form two lengths of lysosomal a-glucosidase, and both N-terminal and C-terminal processing occur. The full sequence can be further processed into a mature form. The 105 kDa GAA can be cleaved into 70 kDa or 76 kDa form.